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Corrositex®: 3 Reasons to Use this Cruelty-Free Corrosivity Testing Method

Corrositex® is a revolutionary dermal corrosion testing assay that replaces the rabbit test that was previously the primary means of determining this. By using Corrositex®, a company is able to determine the dermal corrosivity of its products and allows the assignment of GHS categories, 1A, 1B and 1C, and U.N. Packing group classification for corrosives that are Class 8 hazards. A wide swath of regulatory agencies accept the results of Corrositex® which was developed by In Vitro International. Since it was first granted regulatory approval in 1992, Corrositex® has been accepted by United States agencies such as the FDA, EPA, OSHA, DOT and the Consumer Product Safety Commission. In addition, agencies from across the globe accept the results of Corrositex® including the IATA, EU/OECD, Transport Canada and the European Centre for the Validation of Alternative Methods (ECVAM).

Other Advantages of Using Corrositex®

Not only is the innovative and cruelty-free corrosivity testing method, Corrositex®, accepted by top regulatory agencies across the globe, there are other key reasons for choosing this method instead of rabbit testing.

1. Rapid Results

Getting a product to market is a path that is rife with processes that require significant investments of time including those related to regulations, product development and marketing, to name just a few. Testing for corrosivity using rabbits is a time investment of at least two to four weeks. In contrast, using Corrositex® can provide results in as few as three minutes. A determination when using Corrositex® takes no more than four hours to complete — a significant time savings that can improve a company’s profit margin.

2. Convenient

Using Corrositex® gives companies greater control over their products. There are two ways that Corrositex®  can be used: a sample of the product can be sent to the In Vitro International labs where their highly-trained team tests it fully or the company can obtain Corrositex®  test kits and perform the tests at their own facility.

3. Easy to Use

Corrositex® makes it quick and easy to get the results needed to secure the appropriate regulatory approval. This three-step process begins with a compatibility test between the testing solution and the sample. Next, the test determines the applicable indicator solution to aid in the categorization of the product. Lastly, the sample is exposed to the solution which results in a color change. The time that this change requires is recorded.

In Vitro International is a pioneer in non-invasive and cruelty-free testing that gets products to market quickly. Contact them for more information about Corrositex®, lab services and their other products.

Can New Technology Eventually Eliminate the Need for All Animal Testing?

The vast majority of cosmetic companies no longer need to test their products on animals in order to assure their customers will be safe. Company decision-makers and government officials alike have learned that they can instead rely on technology such as in vitro testing to provide accurate results about the chemicals in their products. But what about the many other industries that still use animals for answers? Will this trend continue across the board? There’s recently been a major push from top levels to implement technology instead of animals in order to find the right answers.

New Roadmaps

A federal committee, named the Interagency Coordinating Committee, recently came out with a report that laid out suggestions on how to replace animal testing with other forms of toxicological testing methods. Right now, there’s a certain amount of confusion about the current state of testing. Different states may require different tests, which can make for inconsistent information depending on the company, product, and location. The federal report wanted a true representation of each and every detail and discrepancy. From there, they developed a strategy for how to promote and convince both politicians and researchers alike that there’s a smarter (and less cruel) way to arrive at the same conclusions.

Understanding Testing

For all of the studies done on animals, there’s unfortunately not a lot of translation between their results and human results. Animal studies often aren’t conducted with the precision and controls that the experiments require to produce consistent results that will apply to humans.While we still don’t test on humans for obvious reasons, researchers continue harming countless animals for surprisingly few benefits. So aside from ending animal cruelty, advanced technology gives testers a better way to regulate their methodology so there’s less room for error (and ultimately, a safer product.)

How the Report Is Structured

The report is encouraging people to remain flexible when it comes to how they approach their testing solutions. Animal testing is a system that has deep roots in so many labs. Regardless of the evidence that animal testing may not be the most efficient solution, it’s always going to be difficult to implement wide-spread change. The federal report is encouraging people to start adopting new technologies such as computational models or tissue chips to replace live animal studies. (Tissue chips are artificial 3D models that replicate human organs.) These new methods may be an initial investment, but they eventually save researchers countless dollars while simultaneously improving every aspect of their organization.

Change Through Encouragement

This report does not mandate change in any way. It doesn’t even give specific ideas about how new legislation should be structured to gradually transition everyone to a new system. It’s merely pointing out that there may be more than one way to solve a problem. However, leaders of the committee do mention that legislation pertaining to animal testing is woefully outdated, which makes it difficult to see the big-picture impact on consumers, companies, and animals. The report stresses the importance of communication among researchers, as well as the benefits of keeping an open mind to alternative testing methods. They suggest that grants should also be changed to reflect the importance and validity of new alternative methods.

Lasting Effects

There’s no reason to delay replacing animal methods with new types of methods for all industries, despite the fact that it will be a major adjustment. Cosmetic companies have been able to make the switch without endangering their customers, profits, or the lives of animals. In fact, animal testing is typically more expensive than alternative methods. This report is a huge step down the road to relying on technology for better results rather than notoriously unreliable animal testing.

In Vitro Testing in China: A Brief Overview

China recently made headlines when it opened a new laboratory that would use in vitro rather than animal testing to determine the safety of certain products, including cosmetics. They’ve also made a promise to explore in vitro for other testing facilities. The country is making these changes because the evidence that’s been presented to officials is irrefutable. In vitro testing is not only effective at determining safety for humans, it’s also cheaper and easier to perform than animal testing. See where China has been, and where it’s going.

The Role of the CFDA

The Chinese Food and Drug Administration (CFDA) has historically considered animal testing to be the only way to authorize the safety of potentially dangerous products. Changing the opinions of officials and lawmakers won’t happen all at once, but it’s clear the nation is open-minded about different testing methods. In 2014, the CFDA made it easier for Chinese cosmetics companies to complete their paperwork. This change subsequently led to the removal of the mandate for animal testing on domestic cosmetic products.

Currently, the CFDA still requires all imported cosmetics to be tested on animals. However, they’ve also recently introduced the same administrative paperwork change for international companies that domestic companies benefited from in 2014. Each change in their regulations shows a major shift in their priorities for the future. Where they may have once thought that animal testing was the only way to keep people from dangerous products, they’re being persuaded by the many studies that prove this is not the case.

Changing Times

Companies have gotten the message when it comes to how the tides are changing, and many professionals in China are working hard to get their facilities ready for alternative methods of testing. Once regulations and laws have been worked out, they’ll be ready to hit the ground running to get new cosmetics to the market. The infrastructure in China right now for in vitro testing is unsurprisingly lacking, but the opening of this new laboratory is a good sign that it won’t stay that way for long.

In fact, China has already approved a phototoxicity in vitro test that tells the manufacturer how chemicals will respond when exposed to light. Certain products that may cause skin or eye irritation can be tested from the comfort and the safety of the lab, without the help of live animals. More and more experts from animal-rights organizations are volunteering their time and expertise to educate officials about the efficacy of in vitro testing to identify potentially harmful substances.

A Brighter Future

Appealing to decision-makers in charge is easier than one might think. While it’s true that animal testing has been a long-accepted practice there, business leaders are simply responding to how practical in vitro testing can be. Not only are animal tests difficult to perform, they’re also not very accurate. Statistics vary across the many tests performed on them, but it’s been established that an animal’s body chemistry is different enough from a human’s that animal testing results are unreliable.

In vitro testing can cost several hundred dollars less than animal testing, and it’s faster. It can test hundreds of substances in a fraction of the time and doesn’t require animal handlers to do so. It should come as little surprise that China has started to let go of its antiquated views on the most effective ways to bring their beauty products from idea to reality. Along with its new laboratory and changing regulations, it’s clear the country is on track towards a better tomorrow.